ACSBG2

Protein-coding gene in the species Homo sapiens
ACSBG2
Identifiers
AliasesACSBG2, BGR, BRGL, PRTD-NY3, PRTDNY3, acyl-CoA synthetase bubblegum family member 2
External IDsOMIM: 614363; MGI: 3587728; HomoloGene: 57133; GeneCards: ACSBG2; OMA:ACSBG2 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for ACSBG2
Genomic location for ACSBG2
Band19p13.3Start6,135,247 bp[1]
End6,193,094 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for ACSBG2
Genomic location for ACSBG2
Band17|17 DStart57,150,103 bp[2]
End57,181,447 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sperm

  • left testis

  • right testis

  • testicle

  • gonad

  • cerebellar hemisphere

  • right hemisphere of cerebellum

  • right coronary artery

  • left uterine tube

  • human kidney
Top expressed in
  • seminiferous tubule

  • spermatid

  • spermatocyte

  • morula

  • blastocyst

  • adrenal gland

  • pancreas

  • islet of Langerhans
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • long-chain fatty acid-CoA ligase activity
  • nucleotide binding
  • acyl-CoA hydrolase activity
  • ligase activity
  • ATP binding
  • catalytic activity
  • very long-chain fatty acid-CoA ligase activity
  • decanoate-CoA ligase activity
Cellular component
  • cytoplasm
  • mitochondrion
  • membrane
  • cytosol
Biological process
  • multicellular organism development
  • cell differentiation
  • metabolism
  • long-chain fatty-acyl-CoA biosynthetic process
  • spermatogenesis
  • fatty acid metabolic process
  • lipid metabolism
  • long-chain fatty acid metabolic process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

81616

328845

Ensembl

ENSG00000130377

ENSMUSG00000024207

UniProt

Q5FVE4

Q2XU92

RefSeq (mRNA)
NM_001289177
NM_001289178
NM_001289179
NM_001289180
NM_030924

NM_001321384

NM_001039114

RefSeq (protein)
NP_001276106
NP_001276107
NP_001276108
NP_001276109
NP_001308313

NP_112186

NP_001034203

Location (UCSC)Chr 19: 6.14 – 6.19 MbChr 17: 57.15 – 57.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Long-chain-fatty-acid—CoA ligase ACSBG2 is an enzyme that in humans is encoded by the ACSBG2 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130377 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024207 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ "Entrez Gene: ACSBG2 acyl-CoA synthetase bubblegum family member 2".

External links

Further reading

  • Pei Z, Jia Z, Watkins PA (Mar 2006). "The second member of the human and murine bubblegum family is a testis- and brainstem-specific acyl-CoA synthetase". The Journal of Biological Chemistry. 281 (10): 6632–41. doi:10.1074/jbc.M511558200. PMID 16371355.
  • Zheng Y, Zhou ZM, Min X, Li JM, Sha JH (Mar 2005). "Identification and characterization of the BGR-like gene with a potential role in human testicular development/spermatogenesis". Asian Journal of Andrology. 7 (1): 21–32. doi:10.1111/j.1745-7262.2005.00014.x. PMID 15685348.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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