ATP13A3

Protein-coding gene in the species Homo sapiens
ATP13A3
Identifiers
AliasesATP13A3, AFURS1, ATPase 13A3
External IDsOMIM: 610232 MGI: 2685387 HomoloGene: 23455 GeneCards: ATP13A3
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for ATP13A3
Genomic location for ATP13A3
Band3q29Start194,402,672 bp[1]
End194,498,364 bp[1]
Gene location (Mouse)
Chromosome 16 (mouse)
Chr.Chromosome 16 (mouse)[2]
Chromosome 16 (mouse)
Genomic location for ATP13A3
Genomic location for ATP13A3
Band16|16 B2Start30,131,241 bp[2]
End30,224,793 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • amniotic fluid

  • palpebral conjunctiva

  • germinal epithelium

  • parietal pleura

  • islet of Langerhans

  • visceral pleura

  • liver

  • tibia

  • right lung
Top expressed in
  • secondary oocyte

  • parotid gland

  • left lung lobe

  • cumulus cell

  • Paneth cell

  • left colon

  • submandibular gland

  • urothelium

  • seminal vesicula

  • thymus
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • nucleotide binding
  • ATPase activity
  • hydrolase activity
  • ATP binding
  • metal ion binding
  • P-type calcium transporter activity
Cellular component
  • integral component of membrane
  • integral component of plasma membrane
  • membrane
  • intracellular membrane-bounded organelle
Biological process
  • cation transport
  • cellular calcium ion homeostasis
  • calcium ion transmembrane transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79572

224088

Ensembl

ENSG00000133657

ENSMUSG00000022533

UniProt

Q9H7F0

Q5XF89

RefSeq (mRNA)

NM_024524
NM_001367549
NM_001374836

NM_001128094
NM_001128096

RefSeq (protein)

NP_078800
NP_001354478
NP_001361765

NP_001121566
NP_001121568

Location (UCSC)Chr 3: 194.4 – 194.5 MbChr 16: 30.13 – 30.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable cation-transporting ATPase 13A3 is an enzyme that in humans is encoded by the ATP13A3 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133657 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022533 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Habtemichael N, Kovacs G (Feb 2002). "Cloning the AFURS1 gene which is up-regulated in senescent human parenchymal kidney cells". Gene. 283 (1–2): 271–5. doi:10.1016/S0378-1119(01)00881-2. PMID 11867234.
  6. ^ "Entrez Gene: ATP13A3 ATPase type 13A3".

External links

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Wick M, Bürger C, Brüsselbach S, et al. (1994). "Identification of serum-inducible genes: different patterns of gene regulation during G0→S and G1→S progression". J. Cell Sci. 107 (1): 227–39. doi:10.1242/jcs.107.1.227. PMID 8175911.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode:2006Natur.440.1194M. doi:10.1038/nature04728. PMID 16641997.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.


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