KIF16B

Protein-coding gene in the species Homo sapiens
KIF16B
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2V14

Identifiers
AliasesKIF16B, C20orf23, KISC20ORF, SNX23, kinesin family member 16B
External IDsOMIM: 618171 MGI: 1098240 HomoloGene: 135708 GeneCards: KIF16B
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for KIF16B
Genomic location for KIF16B
Band20p12.1Start16,272,104 bp[1]
End16,573,448 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for KIF16B
Genomic location for KIF16B
Band2|2 G1Start142,617,474 bp[2]
End142,901,531 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • jejunal mucosa

  • Achilles tendon

  • rectum

  • left adrenal gland

  • gastrocnemius muscle

  • duodenum

  • tibia

  • stromal cell of endometrium

  • biceps brachii
Top expressed in
  • submandibular gland

  • seminal vesicula

  • parotid gland

  • sternocleidomastoid muscle

  • stria vascularis

  • intercostal muscle

  • vastus lateralis muscle

  • digastric muscle

  • triceps brachii muscle

  • lacrimal gland
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • nucleotide binding
  • microtubule motor activity
  • phosphatidylinositol-3-phosphate binding
  • microtubule binding
  • phosphatidylinositol-3,5-bisphosphate binding
  • phosphatidylinositol-3,4-bisphosphate binding
  • phosphatidylinositol binding
  • plus-end-directed microtubule motor activity
  • ATP binding
  • phosphatidylinositol-3,4,5-trisphosphate binding
  • lipid binding
  • ATPase activity
Cellular component
  • cytoplasm
  • endosome
  • early endosome membrane
  • membrane
  • kinesin complex
  • early endosome
  • microtubule
  • cytoskeleton
  • cytosol
  • phagocytic vesicle
Biological process
  • endoderm development
  • epidermal growth factor receptor signaling pathway
  • Golgi to endosome transport
  • receptor catabolic process
  • fibroblast growth factor receptor signaling pathway
  • microtubule-based movement
  • early endosome to late endosome transport
  • formation of primary germ layer
  • regulation of receptor recycling
  • cellular response to interferon-gamma
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55614

16558

Ensembl

ENSG00000089177

ENSMUSG00000038844

UniProt

Q96L93

B1AVY7

RefSeq (mRNA)

NM_001199865
NM_001199866
NM_024704

NM_001081133
NM_001355123

RefSeq (protein)

NP_001186794
NP_001186795
NP_078980

NP_001074602
NP_001342052

Location (UCSC)Chr 20: 16.27 – 16.57 MbChr 2: 142.62 – 142.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin family member 16B, also known as KIF16B, is a protein which in humans is encoded by the KIF16B gene.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089177 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038844 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: KIF16B kinesin family member 16B".

Further reading

  • Seet LF, Hong W (2006). "The Phox (PX) domain proteins and membrane traffic". Biochim. Biophys. Acta. 1761 (8): 878–96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399.
  • Miki H, Okada Y, Hirokawa N (2005). "Analysis of the kinesin superfamily: insights into structure and function". Trends Cell Biol. 15 (9): 467–76. doi:10.1016/j.tcb.2005.07.006. PMID 16084724.
  • Worby CA, Dixon JE (2003). "Sorting out the cellular functions of sorting nexins". Nat. Rev. Mol. Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. S2CID 36361630.
  • Vasilescu J, Zweitzig DR, Denis NJ, et al. (2007). "The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells". J. Proteome Res. 6 (1): 298–305. CiteSeerX 10.1.1.401.4220. doi:10.1021/pr060438j. PMID 17203973.
  • Hoepfner S, Severin F, Cabezas A, et al. (2005). "Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B". Cell. 121 (3): 437–50. doi:10.1016/j.cell.2005.02.017. PMID 15882625. S2CID 16764713.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  • Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.

External links

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Kinesin-like protein KIF16B
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