Quinethazone

Chemical compound

C03BA02 (WHO)

Legal statusLegal status

In general: ℞ (Prescription only)

Identifiers

IUPAC name

7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-
6-sulfonamide

CAS Number

73-49-4^Y

PubChem CID

6307

IUPHAR/BPS

7289

DrugBank

DB01325^Y

ChemSpider

6068^Y

UNII

455E0S048W

KEGG

D00461^Y

ChEMBL

ChEMBL1532^Y

CompTox Dashboard (EPA)

DTXSID9023548

ECHA InfoCard100.000.729

Chemical and physical dataFormulaC₁₀H₁₂ClN₃O₃SMolar mass289.73 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

O=S(=O)(c2c(Cl)cc1c(C(=O)NC(N1)CC)c2)N

InChI

InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17)^Y
Key:AGMMTXLNIQSRCG-UHFFFAOYSA-N^Y

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Quinethazone (INN, brand name Hydromox) is a thiazide-like diuretic used to treat hypertension.^[1] Common side effects include dizziness, dry mouth, nausea, and low potassium levels.

References

^ Sandler G (August 1964). "Quinethazone, a new oral diuretic". British Medical Journal. 2 (5404): 288–92. doi:10.1136/bmj.2.5404.288. PMC 1815620. PMID 14160213.