TUBD1

Protein-coding gene in the species Homo sapiens
TUBD1
Identifiers
AliasesTUBD1, TUBD, tubulin delta 1
External IDsOMIM: 607344 MGI: 1891826 HomoloGene: 9443 GeneCards: TUBD1
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for TUBD1
Genomic location for TUBD1
Band17q23.1Start59,859,479 bp[1]
End59,892,945 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for TUBD1
Genomic location for TUBD1
Band11|11 CStart86,435,817 bp[2]
End86,458,186 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • body of pancreas

  • Achilles tendon

  • thymus

  • vagina

  • canal of the cervix

  • islet of Langerhans

  • minor salivary glands

  • amniotic fluid

  • right lobe of thyroid gland
Top expressed in
  • spermatocyte

  • spermatid

  • seminiferous tubule

  • morula

  • sternocleidomastoid muscle

  • secondary oocyte

  • skeletal muscle tissue

  • temporal muscle

  • medial ganglionic eminence

  • yolk sac
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • nucleotide binding
  • GTP binding
  • structural constituent of cytoskeleton
  • GTPase activity
Cellular component
  • centriole
  • microtubule
  • cytoskeleton
  • nucleus
  • nucleoplasm
  • cytoplasm
  • cytosol
  • cilium
  • cell projection
Biological process
  • multicellular organism development
  • microtubule-based process
  • cytoskeleton organization
  • positive regulation of smoothened signaling pathway
  • cell projection organization
  • microtubule cytoskeleton organization
  • mitotic cell cycle
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51174

56427

Ensembl

ENSG00000108423

ENSMUSG00000020513

UniProt

Q9UJT1

Q9R1K7

RefSeq (mRNA)
NM_001193609
NM_001193610
NM_001193611
NM_001193612
NM_001193613

NM_016261

NM_001199045
NM_001199046
NM_001199047
NM_019756

RefSeq (protein)
NP_001180538
NP_001180539
NP_001180540
NP_001180541
NP_001180542

NP_057345

NP_001185974
NP_001185975
NP_001185976
NP_062730

Location (UCSC)Chr 17: 59.86 – 59.89 MbChr 11: 86.44 – 86.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tubulin, delta 1 is a protein in humans that is encoded by the TUBD1 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108423 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020513 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Tubulin, delta 1".

Further reading

  • Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS (July 2002). "SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation". Molecular and Cellular Biology. 22 (13): 4567–78. doi:10.1128/MCB.22.13.4567-4578.2002. PMC 133908. PMID 12052866.
  • Kato A, Nagata Y, Todokoro K (May 2004). "Delta-tubulin is a component of intercellular bridges and both the early and mature perinuclear rings during spermatogenesis". Developmental Biology. 269 (1): 196–205. doi:10.1016/j.ydbio.2004.01.026. PMID 15081367.
  • Chang P, Stearns T (January 2000). "Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology. 2 (1): 30–5. doi:10.1038/71350. PMID 10620804. S2CID 23500269.
  • Sidjanin DJ, Zangerl B, Johnson JL, Xue F, Mellersh C, Ostrander EA, Acland G, Aguirre GD (April 2002). "Cloning of the canine delta tubulin cDNA (TUBD) and mapping to CFA9". Animal Genetics. 33 (2): 161–2. doi:10.1046/j.1365-2052.2002.0831d.x. PMID 12047234.
  • Smrzka OW, Delgehyr N, Bornens M (April 2000). "Tissue-specific expression and subcellular localisation of mammalian delta-tubulin". Current Biology. 10 (7): 413–6. doi:10.1016/s0960-9822(00)00418-8. PMID 10753753. S2CID 15720739.
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