CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza
| CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza homodimer, Mycobacterium tuberculosis | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.8.11 | ||||||||
| CAS broj | 2603088 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza (EC 2.7.8.11, CDP-diglicerid-inozitolna fosfatidiltransferaza, fosfatidilinozitolna sintaza, CDP-diacilglicerol-inozitolna fosfatidiltransferaza, CDP-diglicerid:inozitol transferaza, citidin 5'-difosfo-1,2-diacil-sn-glicerol:mio-inozitol 3-fosfatidiltransferaza, CDP-DG:inozitol transferaza, citidin difosfodiglicerid-inozitolna fosfatidiltransferaza, CDP-diacilglicerol:mio-inozitol-3-fosfatidiltransferaza, CDP-diglicerid-inozitolna transferaza, citidin difosfoglicerid-inozitolna fosfatidiltransferaza, citidin difosfoglicerid-inozitolna transferaza) je enzim sa sistematskim imenom CDP-diacilglicerol:mio-inozitol 3-fosfatidiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CDP-diacilglicerol + mio-inozitol CMP + 1-fosfatidil-1D-mio-inozitol
Reference
- ↑ Bleasdale, J.E., Wallis, P., MacDonald, P.C. and Johnston, J.M. (1979). „Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue”. Biochim. Biophys. Acta 575: 135-147. PMID 41587.
- ↑ Prottey, C. and Hawthorne, J.N. (1967). „The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas”. Biochem. J. 105: 379-392. PMID 4293959.
- ↑ Salway, J.G., Harewood, J.L., Kai, M., White, G.L. and Hawthorne, J.N. (1968). „Enzymes of phosphoinositide metabolism during rat brain development”. J. Neurochem. 15: 221-226. PMID 4295616.
- ↑ Takenawa, T. and Egawa, K. (1977). „CDP-diglyceride:inositol transferase from rat liver. Purification and properties”. J. Biol. Chem. 252: 5419-5423. PMID 18462.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH CDP-diacylglycerol---inositol+3-phosphatidyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
