Glukoza-1-fosfat uridililtransferaza
| Glukoza-1-fosfat uridililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Glukoza-1-fosfat uridililtransferaza oktamer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.7.9 | ||||||||
| CAS broj | 9026-22-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glukoza-1-fosfat uridililtransferaza (EC 2.7.7.9, UDP glukozna pirofosforilaza, glukoza-1-fosfatna uridililtransferaza, UDPG fosforilaza, UDPG pirofosforilaza, uridin 5'-difosfoglukoza pirofosforilaza, uridin difosfoglukozna pirofosforilaza, uridin difosfat-D-glukozna pirofosforilaza, uridin-difosfat glukozna pirofosforilaza) je enzim sa sistematskim imenom UTP:alfa-D-glukoza-1-fosfat uridililtransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UTP + alfa-D-glukoza 1-fosfat difosfat + UDP-glukoza
Reference
- ↑ Kalckar, H.M. (1953). „The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides”. Biochim. Biophys. Acta 12: 250-264. PMID 13115434.
- ↑ Kamogawa, A. and Kurahashi, K. (1965). „Purification and properties of uridinediphosphate glucose pyrophosphorylase from Escherichia coli K12”. J. Biochem. (Tokyo) 57: 758-765. PMID 4284510.
- ↑ Lobelle-Rich, P.A. and Reeves, R.E. (1983). „Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica”. Mol. Biochem. Parasitol. 7: 173-182. PMID 6304512.
- ↑ Smith, E.E.B. and Mills, G.T. (1955). „The uridyl transferase of mammary gland”. Biochim. Biophys. Acta 18: 152-152. PMID 13260264.
- ↑ Turnquist, R.L., Gillett, T.A. and Hansen, R.G. (1974). „Uridine diphosphate glucose pyrophosphorylase. Crystallization and properties of the enzyme from rabbit liver and species comparisons”. J. Biol. Chem. 249: 7695-7700. PMID 4436332.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH UTP---glucose-1-phosphate+uridylyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
