Halopredone

Chemical compound
Halopredone
Clinical data
Other names2-Bromo-6β,9α-difluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (6R,8S,9R,10S,11S,13S,14S,17R)-2-Bromo-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS Number
  • 57781-15-4
PubChem CID
  • 12788355
ChemSpider
  • 19973602
UNII
  • 6F4361R42W
KEGG
  • D08036
ChEMBL
  • ChEMBL3250144
ECHA InfoCard100.055.394 Edit this at Wikidata
Chemical and physical data
FormulaC21H25BrF2O5
Molar mass475.327 g·mol−1
3D model (JSmol)
  • Interactive image
  • C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C[C@H](C4=CC(=O)C(=C[C@@]43C)Br)F)F)O
InChI
  • InChI=1S/C21H25BrF2O5/c1-18-8-16(27)21(24)11(10(18)3-4-20(18,29)17(28)9-25)5-14(23)12-6-15(26)13(22)7-19(12,21)2/h6-7,10-11,14,16,25,27,29H,3-5,8-9H2,1-2H3/t10-,11-,14+,16-,18-,19-,20-,21-/m0/s1
  • Key:MYZDPUZXMFCPMU-LRIWMWCYSA-N

Halopredone is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 619–620. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 509–. ISBN 978-3-88763-075-1.


  • v
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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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