Hydroflumethiazide
Chemical compound
- C03AA02 (WHO)
- 1,1-Dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
- 135-09-1
Y
- 3647
- 7197
- DB00774 Y
- 3521 Y
- 501CFL162R
- D00654 Y
- ChEMBL1763 Y
- DTXSID3023132
- Interactive image
- FC(F)(F)c2c(cc1c(NCNS1(=O)=O)c2)S(=O)(=O)N
InChI
- InChI=1S/C8H8F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,18)14-3-13-5/h1-2,13-14H,3H2,(H2,12,15,16)Y
- Key:DMDGGSIALPNSEE-UHFFFAOYSA-NY
Hydroflumethiazide (or Saluron) is a diuretic.
Synthesis
See also
- Bendroflumethiazide
References
- ^ Holdrege CT, Babel RB, Cheney LC (1959). "Synthesis of Trifluoromethylated Compounds Possessing Diuretic Activity1". Journal of the American Chemical Society. 81 (18): 4807–4810. doi:10.1021/ja01527a015.
- ^ Close WJ, Swett LR, Brady LE, Short JH, Vernsten M (1960). "Synthesis of Potential Diuretic Agents. I. Derivatives of 7-Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-Dioxide". Journal of the American Chemical Society. 82 (5): 1132–1135. doi:10.1021/ja01490a028.
- ^ Novello FC, Bell SC, Abrams EL, Ziegler C, Sprague JM (1960). "Diuretics: 1,2,4-Benzothiadiazine-1,1-dioxides". The Journal of Organic Chemistry. 25 (6): 970–981. doi:10.1021/jo01076a028.
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