Oxprenoate potassium

Chemical compound
Oxprenoate potassium
Clinical data
Other namesRU-28318; 17α-Hydroxy-3-oxo-7α-propylpregn-4-ene-21-carboxylic acid monopotassium salt
Drug classAntimineralocorticoid
Identifiers
  • potassium 3-[(7R,8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
CAS Number
  • 76676-34-1
PubChem CID
  • 23677972
ChemSpider
  • 64295
UNII
  • 167NDD8MTE
Chemical and physical data
FormulaC25H37KO4
Molar mass440.665 g·mol−1
3D model (JSmol)
  • Interactive image
  • CCC[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(CCC(=O)[O-])O)C.[K+]
InChI
  • InChI=1S/C25H38O4.K/c1-4-5-16-14-17-15-18(26)6-10-23(17,2)19-7-11-24(3)20(22(16)19)8-12-25(24,29)13-9-21(27)28;/h15-16,19-20,22,29H,4-14H2,1-3H3,(H,27,28);/q;+1/p-1/t16-,19+,20+,22-,23+,24+,25-;/m1./s1
  • Key:HXJITUGMCJCKCE-UYOQDFFISA-M

Oxprenoate potassium (developmental code name RU-28318) is a synthetic steroidal antimineralocorticoid which was never marketed.[1] The affinities of oxprenoate potassium for the steroid hormone receptors have been reported.[2]

See also

  • Oxprenoate

References

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 922–. ISBN 978-1-4757-2085-3.
  2. ^ Raynaud JP, Fortin M, Hunt P, Ojasoo T, Doré JC, Surcouf E, Mornon JP, et al. (Fondation Princesse Liliane) (1986). "Approaches to drug development using receptors". In Gotto AM, O'Malley BW (eds.). The Role of Receptors in Biology and Medicine: Proceedings of the Ninth Argenteuil Symposium. Raven Press. pp. 65–77. ISBN 978-0-88167-161-2.


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Mineralocorticoid receptor modulators
MRTooltip Mineralocorticoid receptor
Agonists
Antagonists
See also
Receptor/signaling modulators
Mineralocorticoids and antimineralocorticoids
Glucocorticoid receptor modulators
List of corticosteroids


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