Clofezone

Chemical compound
  • M02AA03 (WHO) M01AA05 (WHO)
Legal statusLegal status
  • Discontinued
IdentifiersCAS Number
  • 17449-96-6 ☒N
PubChem CID
  • 6433695
ChemSpider
  • 4938775 checkY
UNII
  • 5RB28NE79Y
CompTox Dashboard (EPA)
  • DTXSID30169831 Edit this at Wikidata
ECHA InfoCard100.037.681 Edit this at Wikidata ☒NcheckY (what is this?)  (verify)

Clofezone (trade name Perclusone) is a drug that was used to treat joint and muscular pain, but is not marketed any more. It is a combination of clofexamide, an antidepressant, and phenylbutazone, a nonsteroidal anti-inflammatory drug (NSAID).[1][2]

References

  1. ^ Berger A, Wachter H, eds. (1998). Hunnius Pharmazeutisches Wörterbuch (in German) (8 ed.). Walter de Gruyter Verlag. p. 343. ISBN 3-11-015793-4.
  2. ^ Reinicke C, Helbing M, Klingenfeld U, Lasaroff I, Wessel G (December 1984). "[Comparative studies on the bioavailability of various drug forms of phenylbutazone and clofezone (Perclusone)]". Die Pharmazie. 39 (12): 824–7. PMID 6241720.
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Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones /
pyrazolidinessalicylatesacetic acid derivatives
and related substancesoxicamspropionic acid
derivatives (profens)n-arylanthranilic
acids (fenamates)COX-2 inhibitors
(coxibs)otherNSAID
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; withdrawn drugs; veterinary use.
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