Fenclozic acid

Chemical compound
Fenclozic acid
Identifiers
  • [2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid
CAS Number
  • 17969-20-9 checkY
PubChem CID
  • 28858
ChemSpider
  • 26843 ☒N
UNII
  • 58SRQ4DV53
CompTox Dashboard (EPA)
  • DTXSID4046157 Edit this at Wikidata
Chemical and physical data
FormulaC11H8ClNO2S
Molar mass253.70 g·mol−1
3D model (JSmol)
  • Interactive image
  • c1cc(ccc1c2nc(cs2)CC(=O)O)Cl
InChI
  • InChI=1S/C11H8ClNO2S/c12-8-3-1-7(2-4-8)11-13-9(6-16-11)5-10(14)15/h1-4,6H,5H2,(H,14,15) ☒N
  • Key:APBSKHYXXKHJFK-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Fenclozic acid is an analgesic, antipyretic, and anti-inflammatory drug.[1] It has been withdrawn in 1970 due to jaundice.[2]

References

  1. ^ US 3538107, Hepworth W, Stacey GJ, "Aryl-thiazolyl-acetic acid derivatives", issued 1970, assigned to Imperial Chemical Industries Ltd 
  2. ^ Fung M, Thornton A, Mybeck K, Wu JH, Hornbuckle K, Muniz E (1 January 2001). "Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999". Therapeutic Innovation & Regulatory Science. 35 (1): 293–317. doi:10.1177/009286150103500134. S2CID 73036562.
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Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones /
pyrazolidinessalicylatesacetic acid derivatives
and related substancesoxicamspropionic acid
derivatives (profens)n-arylanthranilic
acids (fenamates)COX-2 inhibitors
(coxibs)otherNSAID
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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