Hispidulin
Names | |
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IUPAC name 4′,5,7-Trihydroxy-6-methoxyflavone | |
Systematic IUPAC name 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one | |
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ECHA InfoCard | 100.229.713 |
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Properties | |
Chemical formula | C16H12O6 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Hispidulin is a naturally occurring flavone with potential antiepileptic activity in rats and gerbils.[1][2] It is found in plants including Grindelia argentina, Arrabidaea chica, Saussurea involucrate, Crossostephium chinense, Artemisia, and Salvia.[3]
Complementary medicine
In traditional and complementary medicine it is claimed to have "antioxidant, antifungal, anti-inflammatory, antimutagenic, and antineoplastic properties".[3]
Notes
- ^ Hispidulin inhibits the release of glutamate in rat cerebrocortical nerve terminals. Lin TY1, Lu CW, Wang CC, Lu JF, Wang SJ. Toxicol Appl Pharmacol. 2012 Sep 1;263(2):233-43. doi: 10.1016/j.taap.2012.06.015. Epub 2012 Jul 1.
- ^ The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood–brain barrier and exhibits anticonvulsive effects, Dominique Kavvadias et al, British Journal of Pharmacology (2004) 142, 811–820
- ^ a b Kanika Patel, Dinesh Kumar Patel, Medicinal importance, pharmacological activities, and analytical aspects of hispidulin: A concise report, Journal of Traditional and Complementary Medicine, 2016, ISSN 2225-4110, https://dx.doi.org/10.1016/j.jtcme.2016.11.003.
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Flavones and their conjugates
Monohydroxyflavone | |
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Dihydroxyflavones | |
Trihydroxyflavones | |
Tetrahydroxyflavones | |
Pentahydroxyflavones |
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O-methylated flavones |
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of apigenin | |
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of baicalein | |
of hypolaetin |
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of luteolin |
- Giraldiin A and B
- Nepitrin
- Oroxindin
- Scutellarin
Theograndin I and II
This article about an aromatic compound is a stub. You can help Wikipedia by expanding it. |
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