Renanolone
Chemical compound
- none
- 3α-hydroxy-5β-pregnane-11,20-dione
- 565-99-1
- 68930
- 16736755
- D8Z6E4IR2J
- DTXSID101024028
- Interactive image
- CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(O)[C@H]3C(=O)C[C@]12C
InChI
- InChI=1S/C20H30O4/c1-11(21)15-5-6-16-14-4-3-12-9-13(22)7-8-20(12,24)18(14)17(23)10-19(15,16)2/h12-16,18,22,24H,3-10H2,1-2H3/t12-,13-,14+,15-,16+,18-,19-,20-/m1/s1
- Key:ICICFVFEPDWWAQ-MNYWXNLXSA-N
Renanolone (INN), or 11-ketopregnanolone, also known as 5β-pregnan-3α-ol-11,20-dione, is a synthetic[citation needed] neuroactive steroid which is described as a general anesthetic but was never introduced for clinical use.[1] Its isomers, alfaxolone and alfadolone, are also general anesthetics, and are known to act as positive allosteric modulators of the GABAA receptor, a property which is likely the case for renanolone as well.
Chemistry
See also
References
- ^ Hill RA, Makin HL, Kirk DN, Murphy GM (23 May 1991). Dictionary of Steroids. CRC Press. p. 592. ISBN 978-0-412-27060-4.
- v
- t
- e
Phenols | |
---|---|
Barbiturates | |
Benzodiazepines | |
Opioids | |
Arylcyclohexylamines | |
Neuroactive steroids | |
Others |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This article about a steroid is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e