Quinaprilat

Chemical compound
  • None
Identifiers
  • (3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
CAS Number
  • 82768-85-2
IUPHAR/BPS
  • 6352
ChemSpider
  • 97106
UNII
  • 34SSX5LDE5
ChEMBL
  • ChEMBL1733
CompTox Dashboard (EPA)
  • DTXSID40868904 Edit this at Wikidata
Chemical and physical dataFormulaC23H26N2O5Molar mass410.470 g·mol−13D model (JSmol)
  • Interactive image
  • C[C@@H](C(=O)N1CC2=CC=CC=C2C[C@H]1C(=O)O)N[C@@H](CCC3=CC=CC=C3)C(=O)O
InChI
  • InChI=1S/C23H26N2O5/c1-15(24-19(22(27)28)12-11-16-7-3-2-4-8-16)21(26)25-14-18-10-6-5-9-17(18)13-20(25)23(29)30/h2-10,15,19-20,24H,11-14H2,1H3,(H,27,28)(H,29,30)/t15-,19-,20-/m0/s1
  • Key:FLSLEGPOVLMJMN-YSSFQJQWSA-N

Quinaprilat is the active metabolite of quinapril.[1]

References

  1. ^ Ferry JJ, Horvath AM, Sedman AJ, Latts JR, Colburn WA (1987). "Influence of food on the pharmacokinetics of quinapril and its active diacid metabolite, CI-928". Journal of Clinical Pharmacology. 27 (5): 397–9. doi:10.1002/j.1552-4604.1987.tb03037.x. PMID 3693584. S2CID 36546103.
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Antihypertensive drugs acting on the renin–angiotensin system (C09)
ACE inhibitors
("-pril")AIIRAs
("-sartan")Renin inhibitors
("-kiren")Dual ACE/NEP inhibitors
Neprilysin inhibitors
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ATRTooltip Angiotensin receptor
Combinations:
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