Zofenoprilat

Zofenoprilat
Names
IUPAC name
(4S)-N-[(2S)-2-Methyl-3-sulfanylpropanoyl]-4-(phenylsulfanyl)-L-proline
Systematic IUPAC name
(2S,4S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]-4-(phenylsulfanyl)pyrrolidine-2-carboxylic acid
Identifiers
CAS Number
  • 75176-37-3
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:82602
ChEMBL
  • ChEMBL16332
ChemSpider
  • 24540938
DrugBank
  • DB08766
PubChem CID
  • 3034048
UNII
  • 4G4WDK2YBS
CompTox Dashboard (EPA)
  • DTXSID50231443 Edit this at Wikidata
InChI
  • InChI=1S/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12-,13-/m0/s1
    Key: UQWLOWFDKAFKAP-DRZSPHRISA-N
  • InChI=1/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12-,13-/m0/s1
    Key: UQWLOWFDKAFKAP-DRZSPHRIBV
  • C[C@H](CS)C(=O)N1C[C@H](C[C@H]1C(O)=O)SC1=CC=CC=C1
Properties
Chemical formula
 C15H19NO3S2
Molar mass 325.44 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound

Zofenoprilat is an angiotensin-converting enzyme inhibitor, and is the free sulfhydryl active metabolite of zofenopril.[1]

References

  1. ^ Subissi, A; Evangelista, S; Giachetti, A (1999). "Preclinical Profile of Zofenopril: An Angiotensin Converting Enzyme Inhibitor with Peculiar Cardioprotective Properties". Cardiovascular Drug Reviews. 17 (2): 115. doi:10.1111/j.1527-3466.1999.tb00008.x.
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ATRTooltip Angiotensin receptorCombinations:


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