60S ribosomal protein L30

RPL30
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3VI6, 4UG0, 4V6X, 5AJ0, 3J92, 4UJC, 3J7P, 4UJE, 3J7Q, 3J7R, 4D67, 4UJD, 4V5Z, 4D5Y, 3J7O
Identifiers
Aliases	RPL30, L30, ribosomal protein L30
External IDs	OMIM: 180467; MGI: 98037; HomoloGene: 766; GeneCards: RPL30; OMA:RPL30 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q22.2 Start 98,024,851 bp[1] End 98,046,469 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 B3.1|15 14.33 cM Start 34,440,651 bp[2] End 34,443,786 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parietal pleura urethra skin of hip germinal epithelium left ovary skin of thigh secondary oocyte lactiferous duct right ovary caput epididymis Top expressed in ventricular zone yolk sac neural layer of retina embryo embryo lip morula blastocyst dentate gyrus of hippocampal formation granule cell muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural constituent of ribosome protein binding RNA binding selenocysteine insertion sequence binding Cellular component cytosol ribosome membrane focal adhesion intracellular anatomical structure extracellular exosome nucleus extracellular matrix cytosolic large ribosomal subunit postsynaptic density polysomal ribosome Biological process protein biosynthesis viral transcription SRP-dependent cotranslational protein targeting to membrane translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing antimicrobial humoral immune response mediated by antimicrobial peptide cytoplasmic translation liver regeneration positive regulation of selenocysteine incorporation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6156 19946 Ensembl ENSG00000156482 ENSMUSG00000058600 UniProt P62888 P62889 RefSeq (mRNA) NM_000989 NM_001163485 NM_009083 RefSeq (protein) NP_000980 NP_001156957 NP_033109 Location (UCSC) Chr 8: 98.02 – 98.05 Mb Chr 15: 34.44 – 34.44 Mb PubMed search [3] [4]
Wikidata
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60S ribosomal protein L30 is a protein that in humans is encoded by the RPL30 gene.^[5][6]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30E family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U72 small nucleolar RNA gene, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]

References

Further reading

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