RRP15

Protein-coding gene in the species Homo sapiens
RRP15
Identifiers
AliasesRRP15, KIAA0507, CGI-115, ribosomal RNA processing 15 homolog
External IDsOMIM: 611193; MGI: 1914473; HomoloGene: 32293; GeneCards: RRP15; OMA:RRP15 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for RRP15
Genomic location for RRP15
Band1q41Start218,285,293 bp[1]
End218,337,983 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for RRP15
Genomic location for RRP15
Band1|1 H5Start186,453,175 bp[2]
End186,481,555 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • Achilles tendon

  • cartilage tissue

  • testicle

  • germinal epithelium

  • gastrocnemius muscle

  • right ventricle

  • palpebral conjunctiva

  • gonad

  • biceps brachii
Top expressed in
  • primitive streak

  • epiblast

  • embryo

  • embryo

  • abdominal wall

  • somite

  • morula

  • endothelial cell of lymphatic vessel

  • Gonadal ridge

  • hair follicle
More reference expression data
BioGPS


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

51018

67223

Ensembl

ENSG00000067533

ENSMUSG00000001305

UniProt

Q9Y3B9

Q9CYX7

RefSeq (mRNA)

NM_016052

NM_026041

RefSeq (protein)

NP_057136

NP_080317

Location (UCSC)Chr 1: 218.29 – 218.34 MbChr 1: 186.45 – 186.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RRP15-like protein is a protein that in humans is encoded by the RRP15 gene.[5][6]

This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000067533 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001305 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ De Marchis ML, Giorgi A, Schinina ME, Bozzoni I, Fatica A (Mar 2005). "Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation". RNA. 11 (4): 495–502. doi:10.1261/rna.7200205. PMC 1370738. PMID 15769876.
  6. ^ a b "Entrez Gene: RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)".

Further reading

  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
  • Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  • Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.


  • v
  • t
  • e
Proteins
Initiation factor
Bacterial
Mitochondrial
Archaeal
  • aIF1
  • aIF2
  • aIF5
  • aIF6
Eukaryotic
eIF1
eIF2
eIF3
eIF4
eIF5
eIF6
Elongation factor
Bacterial/​Mitochondrial
Archaeal/​Eukaryotic
Release factor
Ribosomal Proteins
Cytoplasmic
60S subunit
40S subunit
Mitochondrial
39S subunit
28S subunit
Other concepts
Stub icon

This protein-related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e
Stub icon

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e