Probable ribosome biogenesis protein RLP24

Protein-coding gene in the species Homo sapiens
RSL24D1
Identifiers
AliasesRSL24D1, C15orf15, HRP-L30-iso, L30, RLP24, RPL24, RPL24L, TVAS3, ribosomal L24 domain containing 1
External IDsOMIM: 613262; MGI: 2681840; HomoloGene: 9462; GeneCards: RSL24D1; OMA:RSL24D1 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for RSL24D1
Genomic location for RSL24D1
Band15q21.3Start55,180,806 bp[1]
End55,197,049 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for RSL24D1
Genomic location for RSL24D1
Band9|9 DStart73,020,708 bp[2]
End73,030,615 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • germinal epithelium

  • Achilles tendon

  • parietal pleura

  • cartilage tissue

  • tibia

  • ganglionic eminence

  • amniotic fluid

  • ventricular zone

  • epithelium of nasopharynx

  • tail of epididymis
Top expressed in
  • morula

  • epiblast

  • embryo

  • embryo

  • ventricular zone

  • neural tube

  • blastocyst

  • ganglionic eminence

  • yolk sac

  • spermatid
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • structural constituent of ribosome
  • protein binding
  • RNA binding
Cellular component
  • cytosolic large ribosomal subunit
  • ribosome
  • nucleolus
  • intracellular anatomical structure
  • nucleus
Biological process
  • assembly of large subunit precursor of preribosome
  • protein biosynthesis
  • ribosomal large subunit assembly
  • ribosome biogenesis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51187

225215

Ensembl

ENSG00000137876

ENSMUSG00000032215

UniProt

Q9UHA3

Q99L28

RefSeq (mRNA)

NM_016304

NM_198609

RefSeq (protein)

NP_057388

NP_941011

Location (UCSC)Chr 15: 55.18 – 55.2 MbChr 9: 73.02 – 73.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable ribosome biogenesis protein RLP24 is a protein that in humans is encoded by the RSL24D1 gene.[5][6][7]

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137876 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032215 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Saveanu C, Namane A, Gleizes PE, Lebreton A, Rousselle JC, Noaillac-Depeyre J, Gas N, Jacquier A, Fromont-Racine M (Jun 2003). "Sequential protein association with nascent 60S ribosomal particles". Mol Cell Biol. 23 (13): 4449–60. doi:10.1128/MCB.23.13.4449-4460.2003. PMC 164837. PMID 12808088.
  6. ^ Saveanu C, Bienvenu D, Namane A, Gleizes PE, Gas N, Jacquier A, Fromont-Racine M (Nov 2001). "Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps". EMBO J. 20 (22): 6475–84. doi:10.1093/emboj/20.22.6475. PMC 125736. PMID 11707418.
  7. ^ a b "Entrez Gene: C15orf15 chromosome 15 open reading frame 15".

External links

Further reading

  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.


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Proteins
Initiation factor
Bacterial
Mitochondrial
Archaeal
  • aIF1
  • aIF2
  • aIF5
  • aIF6
Eukaryotic
eIF1
eIF2
eIF3
eIF4
eIF5
eIF6
Elongation factor
Bacterial/​Mitochondrial
Archaeal/​Eukaryotic
Release factor
Ribosomal Proteins
Cytoplasmic
60S subunit
40S subunit
Mitochondrial
39S subunit
28S subunit
Other concepts
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