KIF18B

Mammalian protein found in homo sapiens
KIF18B
Identifiers
AliasesKIF18B, kinesin family member 18B
External IDsOMIM: 614570; MGI: 2446979; HomoloGene: 15214; GeneCards: KIF18B; OMA:KIF18B - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KIF18B
Genomic location for KIF18B
Band17q21.31Start44,924,709 bp[1]
End44,947,773 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for KIF18B
Genomic location for KIF18B
Band11|11 E1Start102,796,355 bp[2]
End102,815,950 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • trabecular bone

  • secondary oocyte

  • embryo

  • thymus

  • ganglionic eminence

  • bone marrow

  • stromal cell of endometrium

  • bone marrow cells

  • tibia

  • oral cavity
Top expressed in
  • hand

  • spermatid

  • yolk sac

  • oocyte

  • secondary oocyte

  • primitive streak

  • thymus

  • maxillary prominence

  • seminiferous tubule

  • hair follicle
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • nucleotide binding
  • microtubule binding
  • protein binding
  • kinesin binding
  • cytoskeletal motor activity
  • ATP binding
  • microtubule motor activity
  • ATPase activity
  • plus-end-directed microtubule motor activity
Cellular component
  • cytoplasm
  • microtubule end
  • kinesin complex
  • astral microtubule
  • microtubule plus-end
  • microtubule
  • cytoskeleton
  • nucleus
  • cytosol
  • nuclear body
  • mitotic spindle astral microtubule
  • mitotic spindle midzone
Biological process
  • regulation of cell division
  • cell division
  • microtubule-based movement
  • mitotic sister chromatid segregation
  • cell cycle
  • microtubule depolymerization
  • mitotic cell cycle
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

146909

70218

Ensembl

ENSG00000186185

ENSMUSG00000051378

UniProt

Q86Y91

Q6PFD6

RefSeq (mRNA)

NM_001080443
NM_001264573
NM_001265577

NM_197959

RefSeq (protein)

NP_001251503
NP_001252506

NP_932063

Location (UCSC)Chr 17: 44.92 – 44.95 MbChr 11: 102.8 – 102.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin family member 18B (KIF18B), also known as kinesin-8, is a human protein encoded by the KIF18B gene. It is part of the kinesin family of motor proteins.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186185 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051378 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • v
  • t
  • e
Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects