KIF9

Motor protein found in humans
KIF9
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

3NWN

Identifiers
AliasesKIF9, kinesin family member 9
External IDsOMIM: 607910 MGI: 1098237 HomoloGene: 65620 GeneCards: KIF9
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for KIF9
Genomic location for KIF9
Band3p21.31Start47,227,998 bp[1]
End47,283,451 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for KIF9
Genomic location for KIF9
Band9|9 F2Start110,306,026 bp[2]
End110,354,247 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • bronchial epithelial cell

  • sperm

  • caput epididymis

  • right uterine tube

  • corpus epididymis

  • pancreatic ductal cell

  • amniotic fluid

  • parotid gland

  • left lobe of thyroid gland

  • hypothalamus
Top expressed in
  • spermatid

  • spermatocyte

  • seminiferous tubule

  • olfactory epithelium

  • oocyte

  • secondary oocyte

  • utricle

  • morula

  • esophagus

  • superior frontal gyrus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein dimerization activity
  • nucleotide binding
  • microtubule motor activity
  • protein binding
  • microtubule binding
  • ATP binding
  • ATPase activity
Cellular component
  • cytoskeleton
  • vesicle
  • podosome
  • cytoplasm
  • kinesin complex
  • microtubule
Biological process
  • extracellular matrix disassembly
  • regulation of podosome assembly
  • organelle disassembly
  • microtubule-based movement
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

64147

16578

Ensembl

ENSG00000088727

ENSMUSG00000032489

UniProt

Q9HAQ2
Q6PJI1

Q9WV04

RefSeq (mRNA)
NM_001134878
NM_022342
NM_182902
NM_182903
NM_001377474

NM_001377475
NM_001377476
NM_001377477

NM_001163569
NM_010628

RefSeq (protein)
NP_001128350
NP_071737
NP_878905
NP_001364403
NP_001364404

NP_001364405
NP_001364406

NP_001157041
NP_034758

Location (UCSC)Chr 3: 47.23 – 47.28 MbChr 9: 110.31 – 110.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin family member 9 (KIF9), also known as kinesin-9, is a human protein encoded by the KIF9 gene. It is part of the kinesin family of motor proteins.

Function

The beating of the flagella in sperm is regulated by KIF9 activity.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000088727 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032489 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Miyata H, Shimada K, Morohoshi A, Oura S, Matsumura T, Xu Z, et al. (April 2020). "Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa". FASEB Journal. 34 (4): 5389–5400. doi:10.1096/fj.201902755R. PMC 7136151. PMID 32072696.
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Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects


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