Lamin B2

LMNB2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LLL, 5BNW
Identifiers
Aliases	LMNB2, lamin B2, LAMB2, LMN2, EPM9, MCPH27
External IDs	OMIM: 150341; MGI: 96796; HomoloGene: 7818; GeneCards: LMNB2; OMA:LMNB2 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.3 Start 2,427,638 bp[1] End 2,456,959 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 C1|10 39.72 cM Start 80,737,037 bp[2] End 80,754,079 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence secondary oocyte stromal cell of endometrium gastrocnemius muscle left adrenal gland right adrenal gland anterior pituitary left ventricle appendix body of stomach Top expressed in spermatid seminiferous tubule cumulus cell yolk sac renal corpuscle entorhinal cortex lip ganglionic eminence maxillary prominence lens More reference expression data BioGPS n/a
Gene ontology Molecular function structural molecule activity protein binding molecular function Cellular component intermediate filament nucleus membrane nuclear inner membrane lamin filament nuclear envelope nuclear membrane Biological process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84823 16907 Ensembl ENSG00000176619 ENSMUSG00000062075 UniProt Q03252 P21619 RefSeq (mRNA) NM_032737 NM_010722 NM_001347140 RefSeq (protein) NP_116126 NP_001334069 NP_034852 Location (UCSC) Chr 19: 2.43 – 2.46 Mb Chr 10: 80.74 – 80.75 Mb PubMed search [3] [4]
Wikidata
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Lamin B2 is a protein that in humans is encoded by the LMNB2 gene. It is the second of two type B nuclear lamins, and it is associated with laminopathies.

See also

• Lamin B receptor
• Barraquer–Simons syndrome
• Pelger–Huët anomaly

External links

• Lamin+B at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

References

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